Secretagogue, reference only
Ipamorelin
Selective GHS-R1a pentapeptide agonist; triggers pulsatile GH release without elevating cortisol or prolactin.
Ipamorelin is not in our range right now. This page documents it from the literature for research reference only, not for human use. Compounds available to order are listed below.
Specification
- Molecular weight
- 711.85 Da
- Half-life
- 2 h
- Research area
- Secretagogue
Also called NNC 26-0161
~2 h terminal t½ in healthy human volunteers IV; clearance 0.078 L/h/kg, Vss 0.22 L/kg. Gobburu et al., Pharm Res 1999.
About the research
Ipamorelin (NNC 26-0161) is a Novo Nordisk-developed ghrelin-mimetic pentapeptide and one of the cleanest growth-hormone secretagogues characterized. Its receptor selectivity for GHS-R1a — and absence of off-target HPA-axis activation seen with earlier GHRPs — has made it the canonical research tool for studying pulsatile somatotroph signaling and combination protocols with GHRH analogs.
Mechanism, reported research areas, literature dose ranges and co-factor studies are on the research page, with sources. Nothing there is a claim about this product.
Read the Ipamorelin research overview- Pulsatile GH release pharmacodynamics
- Comparator for ghrelin-receptor-biased agonists
- Postoperative ileus and gastric motility models
- Lean-mass and bone-density research in aged rodents
- Reported research areas, from the literature. Not product claims.
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