Secretagogue, reference only
CJC-1295 (no DAC)
Tetrasubstituted GHRH(1-29) analog without albumin tether; ~30-min half-life preserves pulsatile GH release.
CJC-1295 (no DAC) is not in our range right now. This page documents it from the literature for research reference only, not for human use. Compounds available to order are listed below.
Specification
- Molecular weight
- 3,367.95 Da
- Half-life
- 30 min
- Research area
- Secretagogue
Also called Modified GRF 1-29, Mod GRF 1-29, Sermorelin-like analog
~30 min in humans SC (estimated; no formal published PK trial for the no-DAC form). Sermorelin (GHRH 1-29) parent shows t½ ~10–20 min IV. Stability extended over native GHRH via D-Ala2, Gln8, Ala15, Leu27 substitutions resisting DPP-4 and trypsin.
About the research
CJC-1295 without DAC — more accurately Modified GRF (1-29) — is a stabilized GHRH analog with four amino-acid substitutions (D-Ala2, Gln8, Ala15, Leu27) that protect against enzymatic degradation while preserving the short half-life characteristic of native GHRH. It is the standard pulsatile-GH research tool, typically paired with ghrelin-mimetics like ipamorelin to model the synergistic dual-axis stimulation of physiological GH secretion.
Mechanism, reported research areas, literature dose ranges and co-factor studies are on the research page, with sources. Nothing there is a claim about this product.
Read the CJC-1295 (no DAC) research overview- Pulsatile GHRH receptor activation studies
- Stacked protocols with ipamorelin or hexarelin
- Sleep-architecture and slow-wave-sleep research
- Sermorelin/GHRH comparator pharmacodynamics
- Reported research areas, from the literature. Not product claims.
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