Research / other, reference only
Epitalon
Pineal-derived AEDG tetrapeptide; reports TERT upregulation and telomere lengthening in human somatic cell lines.
Epitalon is not in our range right now. This page documents it from the literature for research reference only, not for human use. Compounds available to order are listed below.
Specification
- Molecular weight
- 390.35 Da
- Half-life
- Not established
- Research area
- Research / other
Also called Epithalon, Epithalone, AEDG tetrapeptide
No formal human PK data published; expected very short plasma t½ (minutes) given small molecular size and rapid proteolysis to constituent amino acids (Ala, Glu, Asp, Gly). Most reported activity reflects pharmacodynamic effects outlasting plasma exposure. Khavinson et al., Bull Exp Biol Med 2002+.
Sequence A E D G
About the research
Epitalon is a four-amino-acid synthetic peptide (Ala-Glu-Asp-Gly) developed by Khavinson and colleagues based on bovine pineal extract Epithalamin. It is among the smallest bioactive peptides studied in gerontology, with multi-decade Russian research reporting effects on telomerase activity, melatonin synthesis, and lifespan in aged rodents — though large-scale human PK and outcome data remain limited.
Mechanism, reported research areas, literature dose ranges and co-factor studies are on the research page, with sources. Nothing there is a claim about this product.
Read the Epitalon research overview- Telomerase induction and telomere-length cell-line studies
- Melatonin and circadian-rhythm research in aged rodents
- Cellular senescence and replicative-aging models
- Pineal gland gerontology research
- Reported research areas, from the literature. Not product claims.
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